Sir Arthur Conan Doyle
The author of Sherlock Holmes, did not live in San Francisco. He visited briefly in 1923 while on a lecture tour and spent an evening with Dr. Albert Adams. Sir Arthur Conan Doyle was notoriously credulous and believed strongly in Dr. Adams' claims to be able to diagnose any disease based on the subject's handwriting and cure it by applying radio waves to the spinal cord. These were later proven to be false. Unfortunately, Dr. Abrams died of pneumonia in 1924, just before some of his followers went on trial for fraud.
Although several of Doyle's characters1 lived in San Francisco he did not like the city's moral tone and wrote:
“It is hardly fair to blame America for the state of San Francisco, for its population is cosmopolitan and its seaport attracts the floating vice of the Pacific; but be the cause what it may, there is much room for spiritual betterment.”
1Even including Watson in Angels of Darkness